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中藥標(biāo)準(zhǔn)品

白藜蘆醇

文字:[大][中][小] 2017-4-28    瀏覽次數(shù):1223    


產(chǎn)品編號(hào)
英文名稱
CAS號(hào)
包裝
 Y3870
 Resveratrol
501-36-0
可根據(jù)客戶要求訂制
產(chǎn)品編號(hào):Y3870

英文名稱:Resveratrol
CAS號(hào):501-36-0
分析標(biāo)準(zhǔn)品
分子式 C14H12O3 分子量228.24


基本信息:



密度1.359
存貯條件 儲(chǔ)存溫度-20°C
描述
產(chǎn)品介紹 無(wú)味,完全溶解于乙醇。
別名 芪三酚;3,4',5-三羥基芪;反式-1,2-(3,4',5-三羥基二苯基)乙烯;(E)-5-[2-(4-羥苯基)-乙烯基]-1,3-苯二酚;3,4′,5-Trihydroxy-trans-stilbene;trans-1,2-(3,4',5-Trihydroxydiphenyl)ethylene
生化機(jī)理
Resveratrol is a phenolic phytoalexin found in grape skin and other plants. Resveratrol produced neurotrophic effects on cultured DA neurons. Resveratrol could attenuate oxidant-induced mitochondrial damage in embryonic rat cardiomyocytes by inactivating GSK-3β via cGMP/PKG signaling pathway independent of NO-related mechanism. Because Resveratrol has anti-inflammatory, anti-oxidant, and hypotriglyceridemic effects, its supplementation may beneficially affect the increased cardiovascular risk of healthy smokers. Resveratrol merits investigation as a potential cancer chemopreventive agent in humans. trans-Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. trans-Resveratrol is also a selective inhibitor of cyclooxygenase-1 (COX-1). It inhibits COX and peroxidase activities of COX-1 with ED50 values of 15 and 3.7 M, respectively; with essentially no inhibition of the COX activity
應(yīng)用 COX1選擇性抑制劑。
白藜蘆醇是一種酚類植物抗毒素,發(fā)現(xiàn)于葡萄皮和其他植物中。它具有細(xì)胞內(nèi)抗氧化活性激活去乙?;窼IRT1。白藜蘆醇的抗糖尿病、神經(jīng)保護(hù)和抗脂特性都可能是去乙?;窼IRT1激活所致。


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