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英文名稱Anti-APLP2/FITC
中文名稱:FITC標記的淀粉樣蛋白β前體樣蛋白2抗體
別 名amyloid beta (A4) precursor like protein 2; Amyloid like protein 2; amyloid precursor protein homolog HSD2; Amyloid protein homolog; Amyloid-like protein 2; APLP-2; Aplp2; APLP2_HUMAN; APPH; APPL2; CDEBP; CDEI box binding protein; CDEI box-binding protein.
規(guī)格:100ul
說 明 書100ul
研究領域細胞生物 免疫學 神經(jīng)生物學 Alzheimer's
抗體來源Rabbit
克隆類型Polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Pig, Horse,
產(chǎn)品應用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量80kDa
細胞定位細胞膜
性 狀Lyophilized or Liquid
濃 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human APLP2
亞 型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹background:
APLP2 is a human sperm membrane protein which contains a segment with high homology to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. The gene which encodes APLP2 maps to human chromosome 11q24.
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
Function:
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
Subunit:
Interacts with CPEB1.
Subcellular Location:
Cell membrane. Nucleus.
Tissue Specificity:
Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.
Post-translational modifications:
The BPTI/Kunitz inhibitor domain is O-glycosylated.
中文名稱:FITC標記的淀粉樣蛋白β前體樣蛋白2抗體
別 名amyloid beta (A4) precursor like protein 2; Amyloid like protein 2; amyloid precursor protein homolog HSD2; Amyloid protein homolog; Amyloid-like protein 2; APLP-2; Aplp2; APLP2_HUMAN; APPH; APPL2; CDEBP; CDEI box binding protein; CDEI box-binding protein.
詳細介紹：
規(guī)格:100ul
說 明 書100ul
研究領域細胞生物 免疫學 神經(jīng)生物學 Alzheimer's
抗體來源Rabbit
克隆類型Polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Pig, Horse,
產(chǎn)品應用IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量80kDa
細胞定位細胞膜
性 狀Lyophilized or Liquid
濃 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human APLP2
亞 型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
相關資料：
產(chǎn)品介紹background:
APLP2 is a human sperm membrane protein which contains a segment with high homology to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. The gene which encodes APLP2 maps to human chromosome 11q24.
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
Function:
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
Subunit:
Interacts with CPEB1.
Subcellular Location:
Cell membrane. Nucleus.
Tissue Specificity:
Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.
Post-translational modifications:
The BPTI/Kunitz inhibitor domain is O-glycosylated.
