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ADP核糖基化因子相關(guān)蛋白1

文字:[大][中][小] 2017-5-4    瀏覽次數(shù):1180    

                                                        ADP核糖基化因子相關(guān)蛋白1                                                                                                                                                
英文名稱  Anti-ARFRP1 
中文名稱  ADP核糖基化因子相關(guān)蛋白1 
別    名  ADP ribosylation factor related protein 1; ARF related protein 1; ARF related protein; ARL 18; ARL18; ARP 1; ARP; ARP1; Helicase like protein NHL; MGC6837; SCG10 like protein; ARFRP_HUMAN. 

詳細(xì)介紹:


濃    度  1mg/1ml 
規(guī) 格  0.1ml/200μg 
抗體來源  Rabbit  
克隆類型  polyclonal 
交叉反應(yīng)  Human, Mouse, Rat, Dog, Pig, Horse, Sheep   
產(chǎn)品類型  一抗    
研究領(lǐng)域  細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)運(yùn)蛋白 糖蛋白  
蛋白分子量  predicted molecular weight: 23kDa 
性    狀  Lyophilized or Liquid 
免 疫 原  KLH conjugated synthetic peptide derived from human ARFRP1 
亞    型  IgG 
純化方法  affinity purified by Protein A 
儲(chǔ) 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4 
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500 
(石蠟切片需做抗原修復(fù)) 
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user.  
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

相關(guān)資料:


產(chǎn)品介紹 The ADP-ribosylation factor (ARF) protein family are structurally and functionally conserved members of the Ras superfamily of regulatory GTP-binding proteins. ARFs influence vesicle trafficking and signal transduction in eukaryotic cells and they play a central role in the maintenance of organelle integrity, assembly of coat proteins and activation of phospholipase D (PC-PLD). ARFRP1 (ADP-ribosylation factor related protein 1), also known as ARP or ARL18, is a 201 amino acid membrane-associated GTPase that localizes to the plasma membrane and the Golgi apparatus and is related to the ARF family of regulatory proteins. Expressed in a variety of tissues, ARFRP1 interacts with SYS1 and is thought to be involved in plasma membrane-related signaling events. ARFRP1 exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to a gene cluster on chromosome 20 that is commonly overexpressed in tumors, suggesting a role for ARFRP1 in carcinogenesis.
Function : ARFRP1 (ARF related protein 1) is a membrane-associated GTP-ase and localizes to the plasma membrane. It is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) genes. ARFPR1 is possibly involved in plasma membrane related signaling events. ARFRP1 interacts with SYS1 and is located in Golgi and found in most tissues. 
Subunit : Interacts with SYS1. 
Subcellular Location : Golgi Apparatus
Tissue Specificity : Found in most tissues. 
Similarity : Belongs to the small GTPase superfamily. Arf family. 
Database links : UniProtKB/Swiss-Prot: Q13795.1

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